The complement system is a key component of innate and adaptive immunity and therefore acts as a vital defense against invading pathogens. Deficiencies in the complement system are associated with ...

The human body’s defensive lineup is impressive—from made-to-order antibodies to natural-born killers. Here’s how it wards off sickness in every season. When pathogens invade our bodies—in the form of ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American The very first line of defence against any ...

The story of Q32 Bio, a company that develops therapeutics for inflammatory and autoimmune diseases, started two decades ago. That's when V. Michael Holers, MD, a University of Colorado School of ...

Journal in the field and provides all-inclusive access to the critical pillars of human gene therapy: research, methods, and clinical applications. Recent clinical trials utilizing high doses of adeno ...

The newborn's immune system is a highly specialized mechanism that takes months to mature and become capable of effectively responding to pathogens. During this phase, adequate nutritional support, ...

Smoking tobacco is so harmful to the body that it changes a person’s immune system, leaving them vulnerable to more disease and infection even years after they’ve quit, a new study found. Although ...

Researchers aimed to track the clinical course and characterize the global and COVID-specific immunity in the blood of individuals with long COVID. Two recent studies have analyzed the blood of ...

Immune dysregulation is a hallmark of cancer. We have shown that breast tumours genomically co -evolve with the immune response, resulting in immunoevasion (Sammut et al., Nature Immunology 2024; ...