Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Advances in next-generation sequencing (NGS) technologies have lowered costs and reduced the complexity of DNA and RNA sequencing, enabling new possibilities when studying gene activity. In ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Scaling up single-cell sequencing studies allows scientists to uncover rare cell types, better understand disease states, and track cellular changes over time. However, processing, assaying, and ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

A new study uses single-cell transcriptomics from a 12-week clinical trial to reveal how kimchi influences the immune system. With seasonal shifts increasing the circulation of respiratory infections ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical ...