It is well known that aging brings an increased likelihood of developing cancer. What is not well understood are the cellular and molecular events that initiate the cancer. Now, researchers at the ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

Advances in next-generation sequencing (NGS) technologies have lowered costs and reduced the complexity of DNA and RNA sequencing, enabling new possibilities when studying gene activity. In ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Cancer continues to be one of the most challenging diseases to treat worldwide. The three main methods used to treat cancer ...