This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Advances in next-generation sequencing (NGS) technologies have lowered costs and reduced the complexity of DNA and RNA sequencing, enabling new possibilities when studying gene activity. In ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

While such advances bring with them a breadth of knowledge, the immense complexity of the datasets makes it challenging for scientists to analyze them using current computational methods. Now, ...

A new study uses single-cell transcriptomics from a 12-week clinical trial to reveal how kimchi influences the immune system. With seasonal shifts increasing the circulation of respiratory infections ...

Kimchi may do far more than add flavor to meals—it could help fine-tune the human immune system. A clinical study using ...