Single-cell omic technologies such as single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) have transformed our ability to dissect cellular heterogeneity within complex tissues.

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. These snapshots provide insights into how spatial ...

Scaling up single-cell sequencing studies allows scientists to uncover rare cell types, better understand disease states, and track cellular changes over time. However, processing, assaying, and ...