eLife

Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach

This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...
Scientific Research Publishing

Secure Offline: A Hardware-Bound Cryptographic Framework for Software License Validation in Internet Constrained Educational Environments ()

The system employs HMAC-SHA256 (Hash-based Message Authentication Code using SHA-256) for license integrity verification. SHA-256 refers to the Secure Hash Algorithm producing 256-bit hash values (see ...

Ruby 4.0: A lot of restructuring under the hood, few new features

The new major version with a new JIT compiler, a revised parallelization API, and a maturing type system paves the way for ...